A sensitive and dependable assay for distinguishing hamster and human X-linked steroid sulfatase activity in somatic cell hybrids.


Journal Article

A radioisotopic assay is described to distinguish between Chinese hamster and human steroid sulfatase activity in extracts prepared from hamster X human somatic cell hybrids. This assay is based on different pH optima and provides a sensitive and unambiguous biochemical marker for the short arm of the human X chromosome and as well as for otherwise genetically inactivated X chromosomes in rodent X human hybrids.

Full Text

Cited Authors

  • Willard, HF; Holmes, MT

Published Date

  • January 1, 1984

Published In

Volume / Issue

  • 66 / 2-3

Start / End Page

  • 272 - 275

PubMed ID

  • 6585346

Pubmed Central ID

  • 6585346

Electronic International Standard Serial Number (EISSN)

  • 1432-1203

International Standard Serial Number (ISSN)

  • 0340-6717

Digital Object Identifier (DOI)

  • 10.1007/bf00286615


  • eng