Mammalian chromosome structure.


Journal Article (Review)

The DNA sequences that are necessary for the formation of a functional mammalian chromosome are thought to be the origins of replication, the telomeres and the centromere. Telomere structure is now well understood, with the functional element characterized as the motif (TTAGGG)n. The structures of the DNA regions that contain origins of replication and a centromere are known, but the functionally important elements within these regions are still only poorly defined.

Full Text

Cited Authors

  • Tyler-Smith, C; Willard, HF

Published Date

  • June 1, 1993

Published In

Volume / Issue

  • 3 / 3

Start / End Page

  • 390 - 397

PubMed ID

  • 8353411

Pubmed Central ID

  • 8353411

Electronic International Standard Serial Number (EISSN)

  • 1879-0380

International Standard Serial Number (ISSN)

  • 0959-437X

Digital Object Identifier (DOI)

  • 10.1016/0959-437x(93)90110-b


  • eng