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Clinical and laboratory manifestations of anti-factor V antibodies.

Publication ,  Journal Article
Ortel, TL
Published in: J Lab Clin Med
April 1999

Factor V is a large, multi-domain glycoprotein that exhibits both procoagulant and anticoagulant activity. Anti-factor V antibodies may develop by several mechanisms and, depending on their epitope specificity, may produce hemorrhagic or thromboembolic complications. The clinical laboratory is an essential component in diagnosing these antibodies, and therapeutic management depends on the predominant clinical manifestations.

Duke Scholars

Published In

J Lab Clin Med

DOI

ISSN

0022-2143

Publication Date

April 1999

Volume

133

Issue

4

Start / End Page

326 / 334

Location

United States

Related Subject Headings

  • Thromboembolism
  • Thrombin
  • Structure-Activity Relationship
  • Humans
  • Hemorrhage
  • General Clinical Medicine
  • Factor V
  • Cattle
  • Autoantibodies
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ortel, T. L. (1999). Clinical and laboratory manifestations of anti-factor V antibodies. J Lab Clin Med, 133(4), 326–334. https://doi.org/10.1016/s0022-2143(99)90062-8
Ortel, T. L. “Clinical and laboratory manifestations of anti-factor V antibodies.J Lab Clin Med 133, no. 4 (April 1999): 326–34. https://doi.org/10.1016/s0022-2143(99)90062-8.
Ortel TL. Clinical and laboratory manifestations of anti-factor V antibodies. J Lab Clin Med. 1999 Apr;133(4):326–34.
Ortel, T. L. “Clinical and laboratory manifestations of anti-factor V antibodies.J Lab Clin Med, vol. 133, no. 4, Apr. 1999, pp. 326–34. Pubmed, doi:10.1016/s0022-2143(99)90062-8.
Ortel TL. Clinical and laboratory manifestations of anti-factor V antibodies. J Lab Clin Med. 1999 Apr;133(4):326–334.
Journal cover image

Published In

J Lab Clin Med

DOI

ISSN

0022-2143

Publication Date

April 1999

Volume

133

Issue

4

Start / End Page

326 / 334

Location

United States

Related Subject Headings

  • Thromboembolism
  • Thrombin
  • Structure-Activity Relationship
  • Humans
  • Hemorrhage
  • General Clinical Medicine
  • Factor V
  • Cattle
  • Autoantibodies
  • Animals