Clinical and laboratory manifestations of anti-factor V antibodies.


Journal Article (Review)

Factor V is a large, multi-domain glycoprotein that exhibits both procoagulant and anticoagulant activity. Anti-factor V antibodies may develop by several mechanisms and, depending on their epitope specificity, may produce hemorrhagic or thromboembolic complications. The clinical laboratory is an essential component in diagnosing these antibodies, and therapeutic management depends on the predominant clinical manifestations.

Full Text

Duke Authors

Cited Authors

  • Ortel, TL

Published Date

  • April 1999

Published In

Volume / Issue

  • 133 / 4

Start / End Page

  • 326 - 334

PubMed ID

  • 10218762

Pubmed Central ID

  • 10218762

International Standard Serial Number (ISSN)

  • 0022-2143

Digital Object Identifier (DOI)

  • 10.1016/s0022-2143(99)90062-8


  • eng

Conference Location

  • United States