Clinical and laboratory evaluation of thrombophilia.

Journal Article (Journal Article;Review)

Thrombophilia is the predisposition to venous thromboembolism and is caused by inherited and acquired factors, alone or in combination. With the discovery of APC resistance and the prothrombin gene mutation, more than half of all patients with clinical characteristics of thrombophilia are now diagnosed with an inherited disorder. The hypercoagulable work-up of patients with venous thromboembolism is important, because the causes can influence the duration and management of anticoagulation therapy, as well as affect other decisions regarding life and health issues.

Full Text

Duke Authors

Cited Authors

  • Perry, SL; Ortel, TL

Published Date

  • March 2003

Published In

Volume / Issue

  • 24 / 1

Start / End Page

  • 153 - 170

PubMed ID

  • 12685062

International Standard Serial Number (ISSN)

  • 0272-5231

Digital Object Identifier (DOI)

  • 10.1016/s0272-5231(02)00054-0


  • eng

Conference Location

  • United States