2-tert-butyl-3-methyl-2,3-dihydroimidazol- 4-one-N-oxide: a new nitrone-based chiral glycine equivalent.

Journal Article (Journal Article)

Cycloaddition reactions between a new homochiral imidazolone-derived nitrone afford cycloadducts in high yield and with high stereoselectivity. Subsequent cycloadduct elaboration affords the gamma-lactones of gamma-hydroxy-alpha-amino acids as well as the optically pure amino acids themselves.

Full Text

Duke Authors

Cited Authors

  • Baldwin, SW; Long, A

Published Date

  • May 2004

Published In

Volume / Issue

  • 6 / 10

Start / End Page

  • 1653 - 1656

PubMed ID

  • 15128259

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol049505a


  • eng