Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines.

Journal Article (Journal Article)

Development of DNA typing for Class I HLA alleles has lagged behind that of class II for a variety of technical reasons. Following the recognition of locus specific sequences in the first and the third intron, and acquiring the ability to amplify genomic DNA by intron-based PCR primer, we have devised DNA typing of class I alleles by SSOP and direct sequencing. In this study using these techniques we provide the allelic typing of HLA-A, -B, and -C genes for the B-lymphoblastoid reference cell lines from the Tenth International Histocompatibility Workshop. We also describe some common associations of the C alleles with HLA-A and HLA-B alleles.

Full Text

Duke Authors

Cited Authors

  • Prasad, VK; Yang, SY

Published Date

  • June 1996

Published In

Volume / Issue

  • 47 / 6

Start / End Page

  • 538 - 546

PubMed ID

  • 8813743

International Standard Serial Number (ISSN)

  • 0001-2815

Digital Object Identifier (DOI)

  • 10.1111/j.1399-0039.1996.tb02596.x


  • eng

Conference Location

  • England