TTP following ITP in an HIV-positive boy.

Journal Article (Journal Article)

PURPOSE: To report the previously undescribed development of thrombotic thrombocytopenic purpura (TTP) in a human immunodeficiency virus (HIV)-positive child and discuss the differential diagnosis. PATIENT AND METHODS: Our patient was a 9-year-old boy with vertically acquired HIV infection and a previous history of immune thrombocytopenic purpura (ITP). Initial presentation, difficulty in diagnosis, clinical course, and subsequent outcome are described. RESULTS: Rapid resolution of TTP following plasmapheresis was seen. CONCLUSIONS: Recognition of this treatable though potentially fatal complication in severely ill HIV-infected children requires a high degree of suspicion in view of its diverse clinical manifestations. The long-term outcome may be relatively good.

Full Text

Duke Authors

Cited Authors

  • Prasad, VK; Kim, IK; Farrington, K; Bussel, JB

Published Date

  • November 1996

Published In

Volume / Issue

  • 18 / 4

Start / End Page

  • 384 - 386

PubMed ID

  • 8888747

International Standard Serial Number (ISSN)

  • 1077-4114

Digital Object Identifier (DOI)

  • 10.1097/00043426-199611000-00010


  • eng

Conference Location

  • United States