Three-dimensional magnetic resonance microscopy of the developing chick embryo.

Journal Article (Journal Article)

Magnetic resonance imaging microscopy was performed on live chick embryos. A combination of high gradient strength (0.47 mT/cm), special purpose radiofrequency coils and 3-dimensional Fourier imaging was used to obtain images with effective thickness of 1.25 mm and pixel dimensions as small as 200 mu in the live chick embryo. The signal-to-noise ratio was sufficient to allow unequivocal identification of the individual chambers of the heart, spinal cord, ventricles in the brain, and vascular structures in the liver of a live 11-day embryo. Anatomical assignment was accomplished with the aid of correlated histologic sections. Because there are no external landmarks, the plane of imaging is frequently oblique, making the 3-dimensional acquisition particularly useful.

Full Text

Duke Authors

Cited Authors

  • Bone, SN; Johnson, GA; Thompson, MB

Published Date

  • October 1, 1986

Published In

Volume / Issue

  • 21 / 10

Start / End Page

  • 782 - 787

PubMed ID

  • 3771148

International Standard Serial Number (ISSN)

  • 0020-9996

Digital Object Identifier (DOI)

  • 10.1097/00004424-198610000-00003


  • eng

Conference Location

  • United States