Modified varicella-like syndrome.


Journal Article (Review)

After incidental exposure to natural varicella, up to 18% of vaccinees reported a breakthrough infection known as modified varicella-like syndrome (MVLS) over up to 10 years of postvaccination follow-up, compared with natural varicella occurring in similarly aged unvaccinated children at the rate of 9% per year. Children with MVLS are frequently asymptomatic, and their disease is characterized by having fewer lesions, less fever, and lasting fewer days than natural varicella. When a case of MVLS occurs there are few secondary cases, suggesting that it is infrequently transmitted. Sequelae such as secondary bacterial infection, cerebellar ataxia, encephalitis, and pneumonia occur infrequently.

Full Text

Duke Authors

Cited Authors

  • Clements, DA

Published Date

  • September 1996

Published In

Volume / Issue

  • 10 / 3

Start / End Page

  • 617 - 629

PubMed ID

  • 8856356

Pubmed Central ID

  • 8856356

International Standard Serial Number (ISSN)

  • 0891-5520


  • eng

Conference Location

  • United States