A case-control study examining risk factors for invasive Haemophilus influenzae type b disease in Victoria, Australia 1988-90.

Journal Article (Journal Article)

OBJECTIVE: To determine whether day-care attendance was a risk factor for Haemophilus influenzae type b (Hib) disease, particularly for epiglottitis. METHODOLOGY: A case-control analysis of risk factors for invasive Hib disease was performed in Victoria, Australia between February 1988 and February 1990 prior to the introduction of immunization for Hib. A total of 210 cases and 367 day surgery hospital controls were enrolled prospectively. Data were collected by questionnaire at the time of admission. RESULTS: Logistic regression analysis showed that risk factors for meningitis were day-care attendance, household crowding and recent illness in a sibling. Risk factors for epiglottitis were day-care attendance and mother's birthplace in Australia or New Zealand. CONCLUSIONS: This study confirms that day-care attendance is a risk factor for Hib epiglottitis as well as meningitis. In addition, the mother's birthplace in Australia or New Zealand is a risk factor for epiglottitis in these data. The reason for this latter observation is unclear.

Full Text

Duke Authors

Cited Authors

  • Clements, DA; Weigle, KA; Gilbert, GL

Published Date

  • December 1995

Published In

Volume / Issue

  • 31 / 6

Start / End Page

  • 513 - 518

PubMed ID

  • 8924302

Pubmed Central ID

  • 8924302

International Standard Serial Number (ISSN)

  • 1034-4810

Digital Object Identifier (DOI)

  • 10.1111/j.1440-1754.1995.tb00874.x


  • eng

Conference Location

  • Australia