Genomic structure of the EPHA1 receptor tyrosine kinase gene.
Publication
, Journal Article
Owshalimpur, D; Kelley, MJ
Published in: Mol Cell Probes
June 1999
Some receptor tyrosine kinase genes are mutated in inherited and somatically acquired human cancers. To permit mutational analysis, the complete genomic structure of the human EPHA1 gene on chromosome 7q34 was determined and oligonucleotide pairs were designed to amplify coding regions. The gene contains 18 exons, two more than the related tyrosine kinase, EPHB2. Presumed sequencing errors in the published cDNA sequence of EPHA1 were identified in exons 10 and 11. Availability of this information will facilitate mutational analysis of EPHA1.
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Published In
Mol Cell Probes
DOI
ISSN
0890-8508
Publication Date
June 1999
Volume
13
Issue
3
Start / End Page
169 / 173
Location
England
Related Subject Headings
- Receptor, EphA1
- Receptor Protein-Tyrosine Kinases
- Molecular Sequence Data
- Microbiology
- Humans
- Exons
- Base Sequence
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
- 0304 Medicinal and Biomolecular Chemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Owshalimpur, D., & Kelley, M. J. (1999). Genomic structure of the EPHA1 receptor tyrosine kinase gene. Mol Cell Probes, 13(3), 169–173. https://doi.org/10.1006/mcpr.1999.0228
Owshalimpur, D., and M. J. Kelley. “Genomic structure of the EPHA1 receptor tyrosine kinase gene.” Mol Cell Probes 13, no. 3 (June 1999): 169–73. https://doi.org/10.1006/mcpr.1999.0228.
Owshalimpur D, Kelley MJ. Genomic structure of the EPHA1 receptor tyrosine kinase gene. Mol Cell Probes. 1999 Jun;13(3):169–73.
Owshalimpur, D., and M. J. Kelley. “Genomic structure of the EPHA1 receptor tyrosine kinase gene.” Mol Cell Probes, vol. 13, no. 3, June 1999, pp. 169–73. Pubmed, doi:10.1006/mcpr.1999.0228.
Owshalimpur D, Kelley MJ. Genomic structure of the EPHA1 receptor tyrosine kinase gene. Mol Cell Probes. 1999 Jun;13(3):169–173.
Published In
Mol Cell Probes
DOI
ISSN
0890-8508
Publication Date
June 1999
Volume
13
Issue
3
Start / End Page
169 / 173
Location
England
Related Subject Headings
- Receptor, EphA1
- Receptor Protein-Tyrosine Kinases
- Molecular Sequence Data
- Microbiology
- Humans
- Exons
- Base Sequence
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
- 0304 Medicinal and Biomolecular Chemistry