Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss.

Journal Article (Journal Article)

Desiccation of plants during drought can be detrimental to agricultural production. The phytohormone abscisic acid (ABA) reduces water loss by triggering stomatal pore closure in leaves, a process requiring ion-channel modulation by cytoplasmic proteins. Deletion of the Arabidopsis farnesyltransferase gene ERA1 or application of farnesyltransferase inhibitors resulted in ABA hypersensitivity of guard cell anion-channel activation and of stomatal closing. ERA1 was expressed in guard cells. Double-mutant analyses of era1 with the ABA-insensitive mutants abi1 and abi2 showed that era1 suppresses the ABA-insensitive phenotypes. Moreover, era1 plants exhibited a reduction in transpirational water loss during drought treatment.

Full Text

Duke Authors

Cited Authors

  • Pei, ZM; Ghassemian, M; Kwak, CM; McCourt, P; Schroeder, JI

Published Date

  • October 1998

Published In

Volume / Issue

  • 282 / 5387

Start / End Page

  • 287 - 290

PubMed ID

  • 9765153

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.282.5387.287


  • eng