DNA-templated self-assembly of protein arrays and highly conductive nanowires.


Journal Article

A DNA nanostructure consisting of four four-arm junctions oriented with a square aspect ratio was designed and constructed. Programmable self-assembly of 4 x 4 tiles resulted in two distinct lattice morphologies: uniform-width nanoribbons and two-dimensional nanogrids, which both display periodic square cavities. Periodic protein arrays were achieved by templated self-assembly of streptavidin onto the DNA nanogrids containing biotinylated oligonucleotides. On the basis of a two-step metallization procedure, the 4 x 4 nanoribbons acted as an excellent scaffold for the production of highly conductive, uniform-width, silver nanowires.

Full Text

Duke Authors

Cited Authors

  • Yan, H; Park, SH; Finkelstein, G; Reif, JH; LaBean, TH

Published Date

  • September 2003

Published In

Volume / Issue

  • 301 / 5641

Start / End Page

  • 1882 - 1884

PubMed ID

  • 14512621

Pubmed Central ID

  • 14512621

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.1089389


  • eng