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Contrast enhancement of the liver. Evaluation by automated contiguous pixel search.

Publication ,  Journal Article
Stude, RA; Hedlund, LW; Johnson, GA; Thompson, WM
Published in: Invest Radiol
February 1987

Eight dogs were infused with one of three different contrast agents: meglumine diatrizoate, iosulamide meglumine, or an ethiodized oil emulsion (EOE 13). Image intensity in the liver was evaluated globally and regionally by means of an automated pixel sampling method to determine differences in the rate of enhancement produced by the three agents. The results of the automated method were compared with those of the standard manual cursor method. The automated method showed that liver parenchyma was enhanced uniformly by all three contrast agents. The maximum degree of enhancement (Mean +/- SEM) for the three agents was diatrizoate, 12.0 +/- 3.5 Hounsfield units (HU); iosluamide, 21.3 +/- 3.5 HU; and EOE 13, 37.2 +/- 4.25 HU. With the manual cursor method, contrast enhancement was about 20% more than estimated by the automated method. The automated method is better for evaluating the magnitude and pattern of contrast agent enhancement of the entire liver, since the currently employed cursor technique requires multiple evaluations to evaluate the entire liver.

Duke Scholars

Published In

Invest Radiol

DOI

ISSN

0020-9996

Publication Date

February 1987

Volume

22

Issue

2

Start / End Page

132 / 136

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Liver
  • Ethiodized Oil
  • Dogs
  • Diatrizoate Meglumine
  • Contrast Media
  • Animals
  • 3202 Clinical sciences
 

Citation

APA
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ICMJE
MLA
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Stude, R. A., Hedlund, L. W., Johnson, G. A., & Thompson, W. M. (1987). Contrast enhancement of the liver. Evaluation by automated contiguous pixel search. Invest Radiol, 22(2), 132–136. https://doi.org/10.1097/00004424-198702000-00008
Stude, R. A., L. W. Hedlund, G. A. Johnson, and W. M. Thompson. “Contrast enhancement of the liver. Evaluation by automated contiguous pixel search.Invest Radiol 22, no. 2 (February 1987): 132–36. https://doi.org/10.1097/00004424-198702000-00008.
Stude RA, Hedlund LW, Johnson GA, Thompson WM. Contrast enhancement of the liver. Evaluation by automated contiguous pixel search. Invest Radiol. 1987 Feb;22(2):132–6.
Stude, R. A., et al. “Contrast enhancement of the liver. Evaluation by automated contiguous pixel search.Invest Radiol, vol. 22, no. 2, Feb. 1987, pp. 132–36. Pubmed, doi:10.1097/00004424-198702000-00008.
Stude RA, Hedlund LW, Johnson GA, Thompson WM. Contrast enhancement of the liver. Evaluation by automated contiguous pixel search. Invest Radiol. 1987 Feb;22(2):132–136.

Published In

Invest Radiol

DOI

ISSN

0020-9996

Publication Date

February 1987

Volume

22

Issue

2

Start / End Page

132 / 136

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Liver
  • Ethiodized Oil
  • Dogs
  • Diatrizoate Meglumine
  • Contrast Media
  • Animals
  • 3202 Clinical sciences