Morphologic phenotyping with MR microscopy: the visible mouse.

Journal Article (Journal Article)

A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.

Full Text

Duke Authors

Cited Authors

  • Johnson, GA; Cofer, GP; Gewalt, SL; Hedlund, LW

Published Date

  • March 2002

Published In

Volume / Issue

  • 222 / 3

Start / End Page

  • 789 - 793

PubMed ID

  • 11867802

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiol.2223010531


  • eng

Conference Location

  • United States