Morphologic phenotyping with MR microscopy: the visible mouse.
Journal Article (Journal Article)
A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.
- Johnson, GA; Cofer, GP; Gewalt, SL; Hedlund, LW
- March 2002
Volume / Issue
- 222 / 3
Start / End Page
- 789 - 793
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States