Magnetic resonance imaging in multiple sclerosis: decreased signal in thalamus and putamen.

Journal Article

High-field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white-matter lesions and clinically definite multiple sclerosis delineated a previously undescribed finding of abnormally decreased signal intensity on T2-weighted images in the thalamus and putamen. The decreased signal intensity (preferential decreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.

Full Text

Duke Authors

Cited Authors

  • Drayer, BP; Burger, P; Hurwitz, B; Dawson, D; Cain, J; Leong, J; Herfkens, R; Johnson, GA

Published Date

  • October 1, 1987

Published In

Volume / Issue

  • 22 / 4

Start / End Page

  • 546 - 550

PubMed ID

  • 3435073

Pubmed Central ID

  • 3435073

Electronic International Standard Serial Number (EISSN)

  • 1531-8249

International Standard Serial Number (ISSN)

  • 0364-5134

Digital Object Identifier (DOI)

  • 10.1002/ana.410220418


  • eng