Gallbladder density and iodine concentration in humans during oral cholecystography. A comparison of iopanoic acid and iopronic acid.
A comparison of two oral cholecystopaques, iopanoic acid (Telepaque) and iopronic acid (Oravue), was performed using normal volunteers. Using a double-blind crossover design, comparisons were made between the degree of gallbladder opacification and the amount of iodine recovered from the gallbladder. Bile was collected via a double lumen intestinal tube before, during, and after stimulating gallbladder contraction. There were no differences between the two agents in terms of opacification or iodine concentration. Only 19% of the administered dose of either agent was recovered, and the maximum iodine concentration in bile was 10 mg I/ml. The results suggest that this technique has merit for future comparative studies of agents concentrated in the gallbladder.
Duke Scholars
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Iopanoic Acid
- Iodobenzenes
- Iodine
- Humans
- Gallbladder
- Double-Blind Method
- Contrast Media
- Clinical Trials as Topic
- Cholecystography
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Iopanoic Acid
- Iodobenzenes
- Iodine
- Humans
- Gallbladder
- Double-Blind Method
- Contrast Media
- Clinical Trials as Topic
- Cholecystography