Gallbladder density and iodine concentration in humans during oral cholecystography. A comparison of iopanoic acid and iopronic acid.

Journal Article

A comparison of two oral cholecystopaques, iopanoic acid (Telepaque) and iopronic acid (Oravue), was performed using normal volunteers. Using a double-blind crossover design, comparisons were made between the degree of gallbladder opacification and the amount of iodine recovered from the gallbladder. Bile was collected via a double lumen intestinal tube before, during, and after stimulating gallbladder contraction. There were no differences between the two agents in terms of opacification or iodine concentration. Only 19% of the administered dose of either agent was recovered, and the maximum iodine concentration in bile was 10 mg I/ml. The results suggest that this technique has merit for future comparative studies of agents concentrated in the gallbladder.

Full Text

Duke Authors

Cited Authors

  • Thompson, WM; Meyers, WC; Shaw, M; Bates, M; Johnson, GA; Hedlund, LW

Published Date

  • November 1, 1982

Published In

Volume / Issue

  • 17 / 6

Start / End Page

  • 621 - 628

PubMed ID

  • 6759456

Pubmed Central ID

  • 6759456

International Standard Serial Number (ISSN)

  • 0020-9996

Digital Object Identifier (DOI)

  • 10.1097/00004424-198211000-00017


  • eng

Conference Location

  • United States