Skip to main content

EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence.

Publication ,  Journal Article
Gilbert, DG; McClernon, FJ; Rabinovich, NE; Dibb, WD; Plath, LC; Hiyane, S; Jensen, RA; Meliska, CJ; Estes, SL; Gehlbach, BA
Published in: Exp Clin Psychopharmacol
November 1999

Changes in task-related mood and physiology associated with 31 days of smoking abstinence were assessed in smokers, 34 of whom were randomly assigned to a quit group and 22 to a continuing-to-smoke control group. A large financial incentive for smoking abstinence resulted in very low participant attrition. Individuals were tested during prequit baselines and at 3, 10, 17, and 31 days of abstinence. Abstinence was associated with decreases in heart rate and serum cortisol, a slowing of electroencephalogram (EEG) activity, and task-dependent and trait-depression-dependent hemispheric EEG asymmetries. Differences between the quit group and the smoking group showed no tendency to resolve across the 31 days of abstinence. Trait depression and neuroticism correlated with increases in left-relative-to-right frontal EEG slow-wave (low alpha) activity at both 3 and 31 days of abstinence. In contrast, prequit nicotine intake and Fagerström Tolerance scores correlated with alpha asymmetry and with greater EEG slowing only at Day 3. Thus, the effects of smoking abstinence appear to last for at least several months.

Duke Scholars

Published In

Exp Clin Psychopharmacol

DOI

ISSN

1064-1297

Publication Date

November 1999

Volume

7

Issue

4

Start / End Page

427 / 443

Location

United States

Related Subject Headings

  • Theta Rhythm
  • Surveys and Questionnaires
  • Substance-Related Disorders
  • Substance Abuse
  • Smoking Cessation
  • Nicotinic Agonists
  • Nicotine
  • Male
  • Hydrocortisone
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gilbert, D. G., McClernon, F. J., Rabinovich, N. E., Dibb, W. D., Plath, L. C., Hiyane, S., … Gehlbach, B. A. (1999). EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence. Exp Clin Psychopharmacol, 7(4), 427–443. https://doi.org/10.1037//1064-1297.7.4.427
Gilbert, D. G., F. J. McClernon, N. E. Rabinovich, W. D. Dibb, L. C. Plath, S. Hiyane, R. A. Jensen, C. J. Meliska, S. L. Estes, and B. A. Gehlbach. “EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence.Exp Clin Psychopharmacol 7, no. 4 (November 1999): 427–43. https://doi.org/10.1037//1064-1297.7.4.427.
Gilbert DG, McClernon FJ, Rabinovich NE, Dibb WD, Plath LC, Hiyane S, et al. EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence. Exp Clin Psychopharmacol. 1999 Nov;7(4):427–43.
Gilbert, D. G., et al. “EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence.Exp Clin Psychopharmacol, vol. 7, no. 4, Nov. 1999, pp. 427–43. Pubmed, doi:10.1037//1064-1297.7.4.427.
Gilbert DG, McClernon FJ, Rabinovich NE, Dibb WD, Plath LC, Hiyane S, Jensen RA, Meliska CJ, Estes SL, Gehlbach BA. EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence. Exp Clin Psychopharmacol. 1999 Nov;7(4):427–443.

Published In

Exp Clin Psychopharmacol

DOI

ISSN

1064-1297

Publication Date

November 1999

Volume

7

Issue

4

Start / End Page

427 / 443

Location

United States

Related Subject Headings

  • Theta Rhythm
  • Surveys and Questionnaires
  • Substance-Related Disorders
  • Substance Abuse
  • Smoking Cessation
  • Nicotinic Agonists
  • Nicotine
  • Male
  • Hydrocortisone
  • Humans