Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype.
Published
Journal Article
Hippocampal sulcal cavities are usually considered incidental findings on brain MRI. In a group of 92 elderly volunteers, the authors graded the number and size of hippocampal sulcal cavities with brain MRI to obtain a cavity score. Cavity scores increased with age, and were higher in subjects carrying the APOE epsilon4 or epsilon2 alleles than in subjects with the epsilon3/3 genotype. Age-related morphologic changes in the hippocampus may be mediated by the APOE genotype.
Full Text
Duke Authors
Cited Authors
- Barboriak, DP; Doraiswamy, PM; Krishnan, KR; Vidyarthi, S; Sylvester, J; Charles, HC
Published Date
- June 13, 2000
Published In
Volume / Issue
- 54 / 11
Start / End Page
- 2150 - 2153
PubMed ID
- 10851380
Pubmed Central ID
- 10851380
International Standard Serial Number (ISSN)
- 0028-3878
Digital Object Identifier (DOI)
- 10.1212/wnl.54.11.2150
Language
- eng
Conference Location
- United States