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The effect of halothane on cultured fibroblasts and neuroblastoma cells.

Publication ,  Journal Article
Uemura, E; Levin, ED
Published in: Neurosci Lett
September 28, 1992

Halothane exposure over the cultured cells (100 and 1,000 ppm) caused a disruption of the pattern of actin distribution in both fibroblasts and neuroblastoma cells. Neuroblastoma cells exposed to halothane also lost microspikes; however, neurite elongation was not affected by halothane. The present study suggests that halothane induces the functional disruption of actin, resulting in an interference of normal neural development in vivo.

Duke Scholars

Published In

Neurosci Lett

DOI

ISSN

0304-3940

Publication Date

September 28, 1992

Volume

145

Issue

1

Start / End Page

33 / 36

Location

Ireland

Related Subject Headings

  • Tumor Cells, Cultured
  • Rats, Sprague-Dawley
  • Rats
  • Pregnancy
  • Neuroblastoma
  • Nervous System Neoplasms
  • Microtubules
  • Mice
  • Halothane
  • Fibroblasts
 

Citation

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Uemura, E., & Levin, E. D. (1992). The effect of halothane on cultured fibroblasts and neuroblastoma cells. Neurosci Lett, 145(1), 33–36. https://doi.org/10.1016/0304-3940(92)90196-e
Uemura, E., and E. D. Levin. “The effect of halothane on cultured fibroblasts and neuroblastoma cells.Neurosci Lett 145, no. 1 (September 28, 1992): 33–36. https://doi.org/10.1016/0304-3940(92)90196-e.
Uemura E, Levin ED. The effect of halothane on cultured fibroblasts and neuroblastoma cells. Neurosci Lett. 1992 Sep 28;145(1):33–6.
Uemura, E., and E. D. Levin. “The effect of halothane on cultured fibroblasts and neuroblastoma cells.Neurosci Lett, vol. 145, no. 1, Sept. 1992, pp. 33–36. Pubmed, doi:10.1016/0304-3940(92)90196-e.
Uemura E, Levin ED. The effect of halothane on cultured fibroblasts and neuroblastoma cells. Neurosci Lett. 1992 Sep 28;145(1):33–36.
Journal cover image

Published In

Neurosci Lett

DOI

ISSN

0304-3940

Publication Date

September 28, 1992

Volume

145

Issue

1

Start / End Page

33 / 36

Location

Ireland

Related Subject Headings

  • Tumor Cells, Cultured
  • Rats, Sprague-Dawley
  • Rats
  • Pregnancy
  • Neuroblastoma
  • Nervous System Neoplasms
  • Microtubules
  • Mice
  • Halothane
  • Fibroblasts