Transdermal nicotine facilitates smoking cessation.
Published
Journal Article
The efficacy of a transdermal nicotine patch in facilitation of smoking cessation was evaluated in a randomized double-blind trial. Sixty-five smokers who were highly dependent on cigarettes participated in the study, which included a behavioral smoking-cessation program. The rates of continuous abstinence were significantly higher in the nicotine group both initially (55% versus 34%) and at 3 weeks (18% versus 6%). Certain smoking withdrawal symptoms, including negative affect and hypoarousal, were effectively relieved by the nicotine patch. There was a trend toward a reduction in cigarette craving, whereas hunger and habit withdrawal symptoms were not affected. The main side effect associated with the nicotine patch was skin irritation. These findings suggest that a nicotine skin patch may be a useful aid to smoking cessation; however, the combination of other techniques with nicotine replacement may provide a more effective treatment for symptoms such as craving for cigarettes.
Full Text
Duke Authors
Cited Authors
- Rose, JE; Levin, ED; Behm, FM; Adivi, C; Schur, C
Published Date
- March 1990
Published In
Volume / Issue
- 47 / 3
Start / End Page
- 323 - 330
PubMed ID
- 2178852
Pubmed Central ID
- 2178852
International Standard Serial Number (ISSN)
- 0009-9236
Digital Object Identifier (DOI)
- 10.1038/clpt.1990.35
Language
- eng
Conference Location
- United States