Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen----q131) and adenosine deaminase (q131----qter) on chromosome 20.

Journal Article (Journal Article)

The gene loci for S-adenosylhomocysteine hydrolase ( AHCY ) and adenosine deaminase (ADA), two enzymes with related metabolic functions, have both been assigned to human chromosome 20. We have used rodent-human somatic hybrids containing translocations involving human chromosome 20 to more precisely determine the relative locations of the AHCY and ADA loci. Our results assign the AHCY locus to the long arm of chromosome 20, in the region cen---- q131 , and ADA to the region q131 ----qter.

Full Text

Duke Authors

Cited Authors

  • Mohandas, T; Sparkes, RS; Suh, EJ; Hershfield, MS

Published Date

  • 1984

Published In

Volume / Issue

  • 66 / 4

Start / End Page

  • 292 - 295

PubMed ID

  • 6586634

International Standard Serial Number (ISSN)

  • 0340-6717

Digital Object Identifier (DOI)

  • 10.1007/BF00287630

Language

  • eng

Conference Location

  • Germany