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Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients.

Publication ,  Journal Article
Su, ZH; Li, JC
Published in: World journal of gastroenterology : WJG
October 2004

AIM: To investigate the pathogenic mechanism of colon cancer at the molecular level and to elucidate the relationship between intercellular adhesion molecule-1 (ICAM-1) and nm23H(1) genes and Chinese patients with colon cancer. METHODS: DNA was extracted from paraffin-embedded materials. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) was used to analyze MSI and LOH. Expression of ICAM-1 was detected by Envision immuno-histochemistry. Experimental results were analyzed with Leica-Qwin computer imaging techniques and SPSS software of statistics. RESULTS: ICAM-1 expression of lymphatic endothelium was negative in normal colon and positive in colon cancer respectively. The number of lymphatics positive for ICAM-1 was gradually increased with degree of cancer invasion (P

Duke Scholars

Published In

World journal of gastroenterology : WJG

ISSN

1007-9327

Publication Date

October 2004

Volume

10

Issue

19

Start / End Page

2800 / 2804

Location

china

Related Subject Headings

  • Gastroenterology & Hepatology
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Su, Z. H., & Li, J. C. (2004). Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients. World Journal of Gastroenterology : WJG, 10(19), 2800–2804.
Su, Z. H., and J. C. Li. “Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients.World Journal of Gastroenterology : WJG 10, no. 19 (October 2004): 2800–2804.
Su ZH, Li JC. Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients. World journal of gastroenterology : WJG. 2004 Oct;10(19):2800–4.
Su, Z. H., and J. C. Li. “Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients.World Journal of Gastroenterology : WJG, vol. 10, no. 19, Oct. 2004, pp. 2800–04.
Su ZH, Li JC. Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients. World journal of gastroenterology : WJG. 2004 Oct;10(19):2800–2804.

Published In

World journal of gastroenterology : WJG

ISSN

1007-9327

Publication Date

October 2004

Volume

10

Issue

19

Start / End Page

2800 / 2804

Location

china

Related Subject Headings

  • Gastroenterology & Hepatology
  • 1103 Clinical Sciences