Risk factors in necrotizing fasciitis: a case involving Cryptococcus neoformans.

Journal Article (Journal Article)

Necrotizing fasciitis is a destructive soft tissue infection that is most typically caused by group A streptococci or a combination of facultative and anaerobic bacteria. Patients at risk for the development of necrotizing fasciitis often have compromised immune function or poor tissue perfusion. This report describes a case of necrotizing fasciitis caused by Cryptococcus neoformans, a pathogen not previously associated with this primary destructive soft tissue infection. The process occurred in a patient at risk for the development of opportunistic infection. We briefly review the risk factors for the development of necrotizing fasciitis and the typical bacteriologic findings. Cryptococcal infections and their treatment are described. Despite the uncommon pathogen, the treatment of this patient followed established principles-prompt surgical intervention and systemic antimicrobial therapy tailored to the offending organisms.

Full Text

Duke Authors

Cited Authors

  • Marcus, JR; Hussong, JW; Gonzalez, C; Dumanian, GA

Published Date

  • January 1998

Published In

Volume / Issue

  • 40 / 1

Start / End Page

  • 80 - 83

PubMed ID

  • 9464704

International Standard Serial Number (ISSN)

  • 0148-7043

Digital Object Identifier (DOI)

  • 10.1097/00000637-199801000-00018


  • eng

Conference Location

  • United States