Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma.

Journal Article (Journal Article)

Patients with hormonally unresponsive prostatic adenocarcinoma were subjected to a five-drug chemotherapy program using bleomycin, 5-fluorouracil, methotrexate, vincristine, and prednisone. Analysis of survival curves indicated that deletion of an alkylating agent from this five-drug program reduced survival when patients with equal risk factors were compared. Bleomycin was poorly tolerated by this aged population.

Full Text

Duke Authors

Cited Authors

  • Paulson, DF; Walker, RA; Berry, WR; Cox, EB; Hinshaw, W

Published Date

  • May 1, 1981

Published In

Volume / Issue

  • 17 / 5

Start / End Page

  • 443 - 445

PubMed ID

  • 6165129

International Standard Serial Number (ISSN)

  • 0090-4295

Digital Object Identifier (DOI)

  • 10.1016/0090-4295(81)90185-0


  • eng

Conference Location

  • United States