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Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma.

Publication ,  Journal Article
Paulson, DF; Walker, RA; Berry, WR; Cox, EB; Hinshaw, W
Published in: Urology
May 1981

Patients with hormonally unresponsive prostatic adenocarcinoma were subjected to a five-drug chemotherapy program using bleomycin, 5-fluorouracil, methotrexate, vincristine, and prednisone. Analysis of survival curves indicated that deletion of an alkylating agent from this five-drug program reduced survival when patients with equal risk factors were compared. Bleomycin was poorly tolerated by this aged population.

Duke Scholars

Published In

Urology

DOI

ISSN

0090-4295

Publication Date

May 1981

Volume

17

Issue

5

Start / End Page

443 / 445

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Prostatic Neoplasms
  • Male
  • Injections, Intravenous
  • Humans
  • Drug Therapy, Combination
  • Bleomycin
  • Antineoplastic Agents
  • Aged
  • Adenocarcinoma
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Paulson, D. F., Walker, R. A., Berry, W. R., Cox, E. B., & Hinshaw, W. (1981). Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma. Urology, 17(5), 443–445. https://doi.org/10.1016/0090-4295(81)90185-0
Paulson, D. F., R. A. Walker, W. R. Berry, E. B. Cox, and W. Hinshaw. “Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma.Urology 17, no. 5 (May 1981): 443–45. https://doi.org/10.1016/0090-4295(81)90185-0.
Paulson, D. F., et al. “Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma.Urology, vol. 17, no. 5, May 1981, pp. 443–45. Pubmed, doi:10.1016/0090-4295(81)90185-0.
Journal cover image

Published In

Urology

DOI

ISSN

0090-4295

Publication Date

May 1981

Volume

17

Issue

5

Start / End Page

443 / 445

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Prostatic Neoplasms
  • Male
  • Injections, Intravenous
  • Humans
  • Drug Therapy, Combination
  • Bleomycin
  • Antineoplastic Agents
  • Aged
  • Adenocarcinoma