The impact of PSA on prostate cancer management. Can we abandon routine staging pelvic lymphadenectomy?


Journal Article (Review)

Despite a negative metastatic evaluation, up to 100% of patients with high-grade tumors are found to harbor metastatic disease within the pelvic lymph nodes at the time of surgery. This article reviews the literature regarding efforts to refine noninvasive preoperative staging through the use of serum tumor markers, improved radiologic imaging, and histologic analysis of the biopsy specimens. A discussion of the renewed controversy regarding the role of pelvic lymphadenectomy in the management of adenocarcinoma of the prostate follows.

Full Text

Duke Authors

Cited Authors

  • Gingrich, JR; Paulson, DF

Published Date

  • April 1995

Published In

Volume / Issue

  • 4 / 2

Start / End Page

  • 335 - 344

PubMed ID

  • 7540939

Pubmed Central ID

  • 7540939

International Standard Serial Number (ISSN)

  • 1055-3207


  • eng

Conference Location

  • United States