Transglutaminase activity in human brain tumors.


Journal Article

Transglutaminase (TG) activity was measured in tissue samples of 45 human brain tumors (pituitary adenomas, meningiomas and gliomas) obtained during neurosurgery. Biochemical analysis and histopathological classification were carried out in the same samples. Mean enzyme activity was highest in non-glial tumors, but due to a high variability of values no significant changes were found between the various histological groups. Thus, TG activity, although considered to play a role in neoplastic growth, does not represent a biochemical marker of malignancy in human brain tumors.

Full Text

Cited Authors

  • Röhn, G; Ernestus, RI; Schröder, R; Hossmann, KA; Klug, N; Paschen, W

Published Date

  • January 1, 1992

Published In

Volume / Issue

  • 42 /

Start / End Page

  • 155 - 158

PubMed ID

  • 1350103

Pubmed Central ID

  • 1350103

International Standard Serial Number (ISSN)

  • 0567-7556


  • eng