Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control.

Journal Article (Journal Article;Review)

Cyclins and cyclin-dependent kinases (Cdks) are universal regulators of cell cycle progression in eukaryotic cells. Cdk activity is controlled by phosphorylation at three conserved sites, and many of the enzymes that act on these sites have now been identified. Although the biochemistry of Cdk phosphorylation is relatively well understood, the regulatory roles of such phosphorylation are, in many cases, obscure. Recent studies have uncovered new and unexpected potential roles, and prompted re-examination of previously assumed roles, of Cdk phosphorylation.

Full Text

Duke Authors

Cited Authors

  • Lew, DJ; Kornbluth, S

Published Date

  • December 1996

Published In

Volume / Issue

  • 8 / 6

Start / End Page

  • 795 - 804

PubMed ID

  • 8939679

International Standard Serial Number (ISSN)

  • 0955-0674

Digital Object Identifier (DOI)

  • 10.1016/s0955-0674(96)80080-9


  • eng

Conference Location

  • England