A proliferation of cyclins.

Journal Article (Journal Article)

Cyclins are regulatory subunits of the serine/threonine protein kinases that play key roles in cell cycle control. The roster of known cyclins has expanded significantly in the past year, revealing a large and very diverse family of proteins. Although cyclins were originally characterized by their periodic accumulation during interphase and destruction in mitosis (these were the 'mitotic' cyclins that control entry into mitosis), the newly identified cyclins do not conform to this pattern. Here we review what is known about the functions of the nonmitotic cyclins in yeast and in mammalian cells.

Full Text

Duke Authors

Cited Authors

  • Lew, DJ; I Reed, S

Published Date

  • March 1992

Published In

Volume / Issue

  • 2 / 3

Start / End Page

  • 77 - 81

PubMed ID

  • 14731948

Pubmed Central ID

  • 14731948

International Standard Serial Number (ISSN)

  • 0962-8924

Digital Object Identifier (DOI)

  • 10.1016/0962-8924(92)90076-y

Language

  • eng

Conference Location

  • England