Slide culture sensitivity tests.


Journal Article

A new method for slide culture sensitivity tests of Mycobacterium tuberculosis is described in which smear-positive sputum spread on slides is incubated without prior decontamination in a selective lysed human blood medium. Results are available 7 days after setting up the tests and are particularly useful for guiding the treatment of smear-positive patients with a long history of unsuccessful chemotherapy. Drug concentrations and definitions of resistance are suggested for tests against isoniazid, streptomycin, PAS, rifampicin ethambutol and ethionamide. A good correlation was seen between the results of these tests and those of standard indirect sensitivity tests.

Full Text

Cited Authors

  • Dickinson, JM; Allen, BW; Mitchison, DA

Published Date

  • June 1989

Published In

Volume / Issue

  • 70 / 2

Start / End Page

  • 115 - 121

PubMed ID

  • 2515643

Pubmed Central ID

  • 2515643

International Standard Serial Number (ISSN)

  • 0041-3879

Digital Object Identifier (DOI)

  • 10.1016/0041-3879(89)90035-4


  • eng