Systematic assignment of the configuration of flexible natural products by spectroscopic and computational methods: the bistramide C analysis.

Journal Article (Journal Article)

[reaction: see text] The combination of NMR NOE, chemical shift, and J-coupling measurements with molar rotation and circular dichroism (CD) determinations, including RI-DFT BP86/aug-cc-pVDZ calculations, reduced a candidate pool of 1024 possible stereoisomers of (+)-bistramide C to a single absolute configuration assignment for the 10 stereogenic carbons of the marine natural product.

Full Text

Published version (via Digital Object Identifier)

Duke Authors

Beratan, David N.

Cited Authors

Zuber, G; Goldsmith, M-R; Hopkins, TD; Beratan, DN; Wipf, P

Published Date

November 2005

Published In

Organic Letters

Volume / Issue

7 / 23

Start / End Page

5269 - 5272

PubMed ID

16268555

Electronic International Standard Serial Number (EISSN)

1523-7052

International Standard Serial Number (ISSN)

1523-7060

Digital Object Identifier (DOI)

10.1021/ol052154v

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