Systematic assignment of the configuration of flexible natural products by spectroscopic and computational methods: the bistramide C analysis.
Journal Article (Journal Article)
[reaction: see text] The combination of NMR NOE, chemical shift, and J-coupling measurements with molar rotation and circular dichroism (CD) determinations, including RI-DFT BP86/aug-cc-pVDZ calculations, reduced a candidate pool of 1024 possible stereoisomers of (+)-bistramide C to a single absolute configuration assignment for the 10 stereogenic carbons of the marine natural product.
Full Text
Duke Authors
Cited Authors
- Zuber, G; Goldsmith, M-R; Hopkins, TD; Beratan, DN; Wipf, P
Published Date
- November 2005
Published In
Volume / Issue
- 7 / 23
Start / End Page
- 5269 - 5272
PubMed ID
- 16268555
Electronic International Standard Serial Number (EISSN)
- 1523-7052
International Standard Serial Number (ISSN)
- 1523-7060
Digital Object Identifier (DOI)
- 10.1021/ol052154v
Language
- eng