Melatonin secretion after surgery.


Journal Article (Letter)

Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.

Full Text

Cited Authors

  • Cronin, AJ; Keifer, JC; Davies, MF; King, TS; Bixler, EO

Published Date

  • October 7, 2000

Published In

Volume / Issue

  • 356 / 9237

Start / End Page

  • 1244 - 1245

PubMed ID

  • 11072950

Pubmed Central ID

  • 11072950

International Standard Serial Number (ISSN)

  • 0140-6736

Digital Object Identifier (DOI)

  • 10.1016/S0140-6736(00)02795-1


  • eng

Conference Location

  • England