Applications of free-electron lasers in the biological and material sciences.

Journal Article (Review;Journal Article)

Free-Electron Lasers (FELs) collectively operate from the terahertz through the ultraviolet range and via intracavity Compton backscattering into the X-ray and gamma-ray regimes. FELs are continuously tunable and can provide optical powers, pulse structures and polarizations that are not matched by conventional lasers. Representative research in the biological and biomedical sciences and condensed matter and material research are described to illustrate the breadth and impact of FEL applications. These include terahertz dynamics in materials far from equilibrium, infrared nonlinear vibrational spectroscopy to investigate dynamical processes in condensed-phase systems, infrared resonant-enhanced multiphoton ionization for gas-phase spectroscopy and spectrometry, infrared matrix-assisted laser-desorption-ionization and infrared matrix-assisted pulsed laser evaporation for analysis and processing of organic materials, human neurosurgery and ophthalmic surgery using a medical infrared FEL and ultraviolet photoemission electron microscopy for nanoscale characterization of materials and nanoscale phenomena. The ongoing development of ultraviolet and X-ray FELs are discussed in terms of future opportunities for applications research.

Full Text

Duke Authors

Cited Authors

  • Edwards, GS; Allen, SJ; Haglund, RF; Nemanich, RJ; Redlich, B; Simon, JD; Yang, WC

Published Date

  • July 2005

Published In

Volume / Issue

  • 81 / 4

Start / End Page

  • 711 - 735

PubMed ID

  • 15755193

Electronic International Standard Serial Number (EISSN)

  • 1751-1097

International Standard Serial Number (ISSN)

  • 0031-8655

Digital Object Identifier (DOI)

  • 10.1562/2004-11-08-ir-363


  • eng