Complex systems analysis: a tool for shock research.


Journal Article (Review)

For the past century, students of shock have focused research efforts to illuminate specific mechanisms that cause, or fail as a consequence of, circulatory collapse. Although clinical strategies aimed at supporting or restoring individual organ systems have proven effective, many patients succumb to more generalized multiple organ system failure. We suggest that general biological systems failure cannot be interpreted through reliance on reductionist science. We propose that complex systems analysis is an essential tool for shock research and we evaluate its application to genomic technologies.

Full Text

Cited Authors

  • Buchman, TG; Cobb, JP; Lapedes, AS; Kepler, TB

Published Date

  • October 1, 2001

Published In

Volume / Issue

  • 16 / 4

Start / End Page

  • 248 - 251

PubMed ID

  • 11580104

Pubmed Central ID

  • 11580104

International Standard Serial Number (ISSN)

  • 1073-2322

Digital Object Identifier (DOI)

  • 10.1097/00024382-200116040-00002


  • eng

Conference Location

  • United States