Effect of enteral nutrition on human pancreatic secretions.

Journal Article (Journal Article)

The influence on pancreatic secretion of four enteral feeding products was evaluated in a unique patient with an isolated duodenal fistula for whom enteral feeding access was obtained via a gastrostomy with a small Silastic catheter passed through the gastrostomy and through a surgically created gastrojejunostomy. The patient was totally supported by intravenous nutrition during the study. Each enteral feeding solution was administered at full strength at 50 ml/hr for 2 days with a 24-hr collection of pancreatic secretions by the duodenal cutaneous fistula taken on the second day. Infusion of the enteral feeding solutions did not alter volume of fistula drainage. All solutions decreased bicarbonate and amylase secretion but increased lipase and total nitrogen excretion. From this study, it would appear reasonable to administer Vivonex HN and Criticare HN via the jejunum in patients with pancreatic disease, whereas Osmolite would appear less satisfactory, due to its much stronger stimulation of lipase secretion.

Full Text

Duke Authors

Cited Authors

  • Grant, JP; Davey-McCrae, J; Snyder, PJ

Published Date

  • 1987

Published In

Volume / Issue

  • 11 / 3

Start / End Page

  • 302 - 304

PubMed ID

  • 3110448

International Standard Serial Number (ISSN)

  • 0148-6071

Digital Object Identifier (DOI)

  • 10.1177/0148607187011003302


  • eng

Conference Location

  • United States