Cimetidine for stress-ulcer prophylaxis.

Journal Article (Clinical Trial;Journal Article;Review)

Although cimetidine is more effective than a placebo for the prophylaxis of stress-induced ulcers, it has no advantage over titrated antacid dosing. Several comparative studies even suggest that combining cimetidine with antacid is no more effective than use of full-dose antacid. Therefore, we recommend prophylactic use of cimetidine only when very large dosages of antacid are required, in order to minimize acid-base disturbances.

Full Text

Duke Authors

Cited Authors

  • Greene, WL; Bollinger, RR

Published Date

  • July 1984

Published In

Volume / Issue

  • 12 / 7

Start / End Page

  • 571 - 575

PubMed ID

  • 6375965

International Standard Serial Number (ISSN)

  • 0090-3493

Digital Object Identifier (DOI)

  • 10.1097/00003246-198407000-00005


  • eng

Conference Location

  • United States