Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus.

Conference Paper

Glucosinolate profiles differ among Arabidopsis thaliana ecotypes, caused by the composition of alleles at several glucosinolate biosynthetic loci. One of these, GS-Elong, harbors a family of methylthioalkylmalate synthase (MAM) genes that determine the side chain length of aliphatic glucosinolate structures. Fine mapping reveals that GS-Elong constitutes an insect resistance quantitative trait locus, caused by variation in glucosinolate profiles conferred by polymorphism of MAM alleles in this region. A sequence survey of randomly chosen ecotypes indicates that GS-Elong is highly variable among A. thaliana ecotypes: indel polymorphisms are frequent, as well as gene conversion events between gene copies arranged in tandem. Furthermore, statistical methods of molecular population genetics suggest that one of the genes, MAM2, is subject to balancing selection. This may be caused by ecological tradeoffs, i.e., by contrasting physiological effects of glucosinolates on generalist vs. specialist insects.

Full Text

Duke Authors

Cited Authors

  • Kroymann, J; Donnerhacke, S; Schnabelrauch, D; Mitchell-Olds, T

Published Date

  • November 2003

Published In

Volume / Issue

  • 100 Suppl 2 /

Start / End Page

  • 14587 - 14592

PubMed ID

  • 14506289

Pubmed Central ID

  • PMC304123

Electronic International Standard Serial Number (EISSN)

  • 1091-6490

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.1734046100