The molecular basis of quantitative genetic variation in natural populations.

Journal Article (Journal Article)

DNA markers allow us to study quantitative trait loci (QTL) - the genes that control adaptation and quantitative variation. Experiments can map the genes responsible for quantitative variation and address the evolutionary and ecological significance of this variation. Recent studies suggest that major genes segregate within and among natural populations. It is now feasible to study the genes that cause morphological variation, life history trade-offs, heterosis and speciation. These methods can determine the role of epistasis and genotype-by-environment interaction in maintaining genetic variation. QTL mapping is an important tool used to address evolutionary and ecological questions of long-standing interest.

Full Text

Duke Authors

Cited Authors

  • Mitchell-Olds, T

Published Date

  • August 1995

Published In

Volume / Issue

  • 10 / 8

Start / End Page

  • 324 - 328

PubMed ID

  • 21237056

Electronic International Standard Serial Number (EISSN)

  • 1872-8383

International Standard Serial Number (ISSN)

  • 0169-5347

Digital Object Identifier (DOI)

  • 10.1016/s0169-5347(00)89119-3


  • eng