In vitro activity of telithromycin against macrolide-susceptible and macrolide-resistant pharyngeal isolates of group A streptococci in the United States.


Journal Article

In vitro susceptibility testing of 2,797 group A streptococcus (GAS) isolates demonstrated that telithromycin was fully active against all macrolide-susceptible strains and among 80 of 115 macrolide-resistant GAS expressing the M phenotype. Telithromycin resistance was identified in 2 of 45 strains expressing the inducible macrolide-lincosamide-streptogramin B phenotype and four of nine isolates expressing the constitutive macrolide-lincosamide-streptogramin B resistance phenotype.

Full Text

Duke Authors

Cited Authors

  • Green, M; Allen, C; Bradley, J; Dashefsky, B; Gilsdorf, JR; Marcon, MJ; Schutze, GE; Smith, C; Walter, E; Martin, JM; Edwards, KA; Barbadora, KA; Rumbaugh, RM; Wald, ER

Published Date

  • June 2005

Published In

Volume / Issue

  • 49 / 6

Start / End Page

  • 2487 - 2489

PubMed ID

  • 15917551

Pubmed Central ID

  • 15917551

International Standard Serial Number (ISSN)

  • 0066-4804

Digital Object Identifier (DOI)

  • 10.1128/AAC.49.6.2487-2489.2005


  • eng

Conference Location

  • United States