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Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion.

Publication ,  Journal Article
Mitchell, TG; Turner, SR
Published in: Sabouraudia
1984

A potent chemotactic activity for neutrophils is detectable in liquid culture filtrates of Blastomyces dermatitidis. The production of this activity is medium-dependent and culture age-dependent. The highest levels of cytotaxin were produced in filtrates of B. dermatitidis grown in tissue culture medium 199 for three or more weeks. This factor(s) stimulates directed as well as random migration. It functions directly and independently of serum. It is stable at -20 degrees C and 56 degrees C, and has a molecular weight greater than 10000 daltons. These properties define a new microbial chemotactic factor.

Duke Scholars

Published In

Sabouraudia

ISSN

0036-2174

Publication Date

1984

Volume

22

Issue

2

Start / End Page

145 / 153

Location

England

Related Subject Headings

  • Temperature
  • Neutrophils
  • Molecular Weight
  • Interleukin-8
  • Humans
  • Culture Media
  • Chemotaxis, Leukocyte
  • Chemotactic Factors
  • Blastomyces
 

Citation

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Mitchell, T. G., & Turner, S. R. (1984). Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion. Sabouraudia, 22(2), 145–153.
Mitchell, T. G., and S. R. Turner. “Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion.Sabouraudia 22, no. 2 (1984): 145–53.
Mitchell TG, Turner SR. Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion. Sabouraudia. 1984;22(2):145–53.
Mitchell, T. G., and S. R. Turner. “Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion.Sabouraudia, vol. 22, no. 2, 1984, pp. 145–53.
Mitchell TG, Turner SR. Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion. Sabouraudia. 1984;22(2):145–153.

Published In

Sabouraudia

ISSN

0036-2174

Publication Date

1984

Volume

22

Issue

2

Start / End Page

145 / 153

Location

England

Related Subject Headings

  • Temperature
  • Neutrophils
  • Molecular Weight
  • Interleukin-8
  • Humans
  • Culture Media
  • Chemotaxis, Leukocyte
  • Chemotactic Factors
  • Blastomyces