Depressive symptoms and nine-year survival of 1,001 male veterans hospitalized with medical illness.


Journal Article

Authors examined effects of depressive symptoms on after-discharge survival of hospitalized medically ill male veterans. Psychosocial and physical health evaluations were performed on a consecutive sample of 1,001 patients ages 20-39 (16%) and 65-102 years (84%). Subjects or surviving family members were later contacted by telephone, and Cox proportional-hazards regression modeled the effects of depressive symptoms on time-to-death, controlling for demographics and social, psychiatric, and physical health. Follow-up was obtained on all 1,001 patients (average observation time, 9 years), during which 667 patients died (67%). Patients with depressive symptoms were significantly less likely to survive. For every 1-point increase on the 12-item Brief Carroll Depression Rating Scale (BCDRS), the hazard of dying increased by 10% (P<0. 0001). Age did not significantly affect the association between depressive symptoms and mortality. Depressive symptoms during acute hospitalization are a predictor of shortened survival.

Full Text

Duke Authors

Cited Authors

  • Koenig, HG; George, LK; Larson, DB; McCullough, ME; Branch, PS; Kuchibhatla, M

Published Date

  • 1999

Published In

Volume / Issue

  • 7 / 2

Start / End Page

  • 124 - 131

PubMed ID

  • 10322239

Pubmed Central ID

  • 10322239

International Standard Serial Number (ISSN)

  • 1064-7481


  • eng

Conference Location

  • England