Skip to main content
Journal cover image

Heterogeneity of tardive dyskinesia. A multivariate analysis.

Publication ,  Journal Article
Glazer, WM; Morgenstern, H; Niedzwiecki, D; Hughes, J
Published in: Br J Psychiatry
February 1988

To determine whether tardive dyskinesia (TD) is a single abnormal movement syndrome or multiple syndromes involving different anatomical areas, we examined 228 out-patients diagnosed with TD at the Connecticut Mental Health Center in New Haven. Application of factor analysis to the seven anatomical severity scores of the Abnormal Involuntary Movement Scale yielded three statistically independent factors involving abnormal movements primarily of the jaw-tongue, face-lips, and extremities-trunk. Using logistic regression to predict the severity of these factors, we found that the severity of the orofacial scores was positively associated with age, schizoaffective or affective disorder, and living alone, while severity of non-orofacial movement was positively associated with current neuroleptic dose, non-use of psychiatric medication, and living alone. Our findings suggest that orofacial and non-orofacial dyskinetic movements may involve distinct clinical syndromes of TD, each having a different set of prognostic and, possibly, aetiological determinants.

Duke Scholars

Published In

Br J Psychiatry

DOI

ISSN

0007-1250

Publication Date

February 1988

Volume

152

Start / End Page

253 / 259

Location

England

Related Subject Headings

  • Tongue
  • Psychotic Disorders
  • Psychiatry
  • Mood Disorders
  • Middle Aged
  • Male
  • Jaw
  • Humans
  • Female
  • Facial Muscles
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Glazer, W. M., Morgenstern, H., Niedzwiecki, D., & Hughes, J. (1988). Heterogeneity of tardive dyskinesia. A multivariate analysis. Br J Psychiatry, 152, 253–259. https://doi.org/10.1192/bjp.152.2.253
Glazer, W. M., H. Morgenstern, D. Niedzwiecki, and J. Hughes. “Heterogeneity of tardive dyskinesia. A multivariate analysis.Br J Psychiatry 152 (February 1988): 253–59. https://doi.org/10.1192/bjp.152.2.253.
Glazer WM, Morgenstern H, Niedzwiecki D, Hughes J. Heterogeneity of tardive dyskinesia. A multivariate analysis. Br J Psychiatry. 1988 Feb;152:253–9.
Glazer, W. M., et al. “Heterogeneity of tardive dyskinesia. A multivariate analysis.Br J Psychiatry, vol. 152, Feb. 1988, pp. 253–59. Pubmed, doi:10.1192/bjp.152.2.253.
Glazer WM, Morgenstern H, Niedzwiecki D, Hughes J. Heterogeneity of tardive dyskinesia. A multivariate analysis. Br J Psychiatry. 1988 Feb;152:253–259.
Journal cover image

Published In

Br J Psychiatry

DOI

ISSN

0007-1250

Publication Date

February 1988

Volume

152

Start / End Page

253 / 259

Location

England

Related Subject Headings

  • Tongue
  • Psychotic Disorders
  • Psychiatry
  • Mood Disorders
  • Middle Aged
  • Male
  • Jaw
  • Humans
  • Female
  • Facial Muscles