Skip to main content
Journal cover image

Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.

Publication ,  Journal Article
Kypson, AP; Morphew, E; Jones, R; Gottfried, MR; Seigler, HF
Published in: J Surg Oncol
February 2003

The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature. Immunohistochemistry for a bone morphogenic protein (BMP-2) and fibroblast growth factor (FGF-2), both of which induce and stimulate bone formation, was performed and revealed overexpression of BMP-2 by the tumor cells, elucidating a possible mechanism which up to now had been based merely on speculation.

Duke Scholars

Published In

J Surg Oncol

DOI

ISSN

0022-4790

Publication Date

February 2003

Volume

82

Issue

2

Start / End Page

132 / 136

Location

United States

Related Subject Headings

  • Uracil
  • Treatment Outcome
  • Transforming Growth Factor beta
  • Rectal Neoplasms
  • Radiotherapy, Adjuvant
  • Ossification, Heterotopic
  • Oncology & Carcinogenesis
  • Neoadjuvant Therapy
  • Immunohistochemistry
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kypson, A. P., Morphew, E., Jones, R., Gottfried, M. R., & Seigler, H. F. (2003). Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol, 82(2), 132–136. https://doi.org/10.1002/jso.10181
Kypson, Alan P., Emilie Morphew, Relief Jones, Marcia R. Gottfried, and Hilliard F. Seigler. “Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.J Surg Oncol 82, no. 2 (February 2003): 132–36. https://doi.org/10.1002/jso.10181.
Kypson AP, Morphew E, Jones R, Gottfried MR, Seigler HF. Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol. 2003 Feb;82(2):132–6.
Kypson, Alan P., et al. “Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.J Surg Oncol, vol. 82, no. 2, Feb. 2003, pp. 132–36. Pubmed, doi:10.1002/jso.10181.
Kypson AP, Morphew E, Jones R, Gottfried MR, Seigler HF. Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol. 2003 Feb;82(2):132–136.
Journal cover image

Published In

J Surg Oncol

DOI

ISSN

0022-4790

Publication Date

February 2003

Volume

82

Issue

2

Start / End Page

132 / 136

Location

United States

Related Subject Headings

  • Uracil
  • Treatment Outcome
  • Transforming Growth Factor beta
  • Rectal Neoplasms
  • Radiotherapy, Adjuvant
  • Ossification, Heterotopic
  • Oncology & Carcinogenesis
  • Neoadjuvant Therapy
  • Immunohistochemistry
  • Humans