Lentigo maligna melanoma of the head and neck.

Journal Article (Journal Article)

Historically, lentigo maligna melanoma has been considered a "favorable" histological type of melanoma, and treatment by wide local excision was considered curative. A retrospective multivariate analysis of 143 head and neck patients with stage I lentigo maligna melanoma was performed from a database of 1067 head and neck patients followed at Duke Medical Center. Fifty-six percent of all lentigo maligna melanomas presented with lesions deeper than 0.76 mm, and 8% presented with stage II or III disease. Recurrent disease occurred in 45% of stage I patients, with a 5-year disease-free interval of 6 years and a median survival time of 10 years. Multivariate analysis demonstrated no significant difference in disease-free interval or survival by histological subtype. The data suggest that treatment should be based on tumor thickness and not histologic subtype.

Full Text

Duke Authors

Cited Authors

  • Langford, FP; Fisher, SR; Molter, DW; Seigler, HF

Published Date

  • May 1993

Published In

Volume / Issue

  • 103 / 5

Start / End Page

  • 520 - 524

PubMed ID

  • 8483369

International Standard Serial Number (ISSN)

  • 0023-852X

Digital Object Identifier (DOI)

  • 10.1288/00005537-199305000-00007


  • eng

Conference Location

  • United States