Immunological consequences of transplanting rat insulinomas.
Publication
, Journal Article
Reintgen, D; Croker, B; Vervaert, C; Feldman, J; Seigler, HF
Published in: Transplantation
July 1980
We investigated the genetics of transplanting a NEDH rat insulinoma in various donor-recipient combinations. The insulinoma survived indefinitely when it was transplanted in the NEDH strain. Mean survival times of 8.6 +/- 1.2 and 3.3 +/- 1.0 days were recorded in allogeneic and xenogeneic combinations, respectively. No prolongation of mean survival time was found when the rat insulinoma was first passed through the athymic nude mouse and then transplanted as either an allograft or xenograft. The findings of the major histocompatibility antigen (Ag-B7) on the original insulinoma and the tumor that had been passed through the nude mouse demonstrates no demonstrable loss of transplantation antigens during passage.
Duke Scholars
Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
July 1980
Volume
30
Issue
1
Start / End Page
16 / 22
Location
United States
Related Subject Headings
- Surgery
- Rats, Inbred Strains
- Rats
- Pancreatic Neoplasms
- Pancreas
- Neoplasm Transplantation
- Mice, Nude
- Mice, Inbred Strains
- Mice
- Histocompatibility Antigens
Citation
APA
Chicago
ICMJE
MLA
NLM
Reintgen, D., Croker, B., Vervaert, C., Feldman, J., & Seigler, H. F. (1980). Immunological consequences of transplanting rat insulinomas. Transplantation, 30(1), 16–22. https://doi.org/10.1097/00007890-198007000-00004
Reintgen, D., B. Croker, C. Vervaert, J. Feldman, and H. F. Seigler. “Immunological consequences of transplanting rat insulinomas.” Transplantation 30, no. 1 (July 1980): 16–22. https://doi.org/10.1097/00007890-198007000-00004.
Reintgen D, Croker B, Vervaert C, Feldman J, Seigler HF. Immunological consequences of transplanting rat insulinomas. Transplantation. 1980 Jul;30(1):16–22.
Reintgen, D., et al. “Immunological consequences of transplanting rat insulinomas.” Transplantation, vol. 30, no. 1, July 1980, pp. 16–22. Pubmed, doi:10.1097/00007890-198007000-00004.
Reintgen D, Croker B, Vervaert C, Feldman J, Seigler HF. Immunological consequences of transplanting rat insulinomas. Transplantation. 1980 Jul;30(1):16–22.
Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
July 1980
Volume
30
Issue
1
Start / End Page
16 / 22
Location
United States
Related Subject Headings
- Surgery
- Rats, Inbred Strains
- Rats
- Pancreatic Neoplasms
- Pancreas
- Neoplasm Transplantation
- Mice, Nude
- Mice, Inbred Strains
- Mice
- Histocompatibility Antigens