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The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions.

Publication ,  Journal Article
Seigler, HF; Ward, FE; Amos, DB; Phaup, MB; Stickel, DL
Published in: J Exp Med
March 1, 1971

The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1-12 as well as other nondefined specificities. Mixed leukocyte reactions were also studied in this series and the correlations between the mixed leukocyte reactions with skin graft survival times, individual HL-A specificities, and the number of incompatible HL-A alleles are reported. Comments concerning the interpretation and quantitation of the mixed leukocyte reactions are discussed.

Duke Scholars

Published In

J Exp Med

DOI

ISSN

0022-1007

Publication Date

March 1, 1971

Volume

133

Issue

3

Start / End Page

411 / 423

Location

United States

Related Subject Headings

  • Time Factors
  • Skin Transplantation
  • Leukocytes
  • Immunology
  • Immunogenetics
  • Humans
  • Histocompatibility
  • Antigens
  • Alleles
  • 42 Health sciences
 

Citation

APA
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ICMJE
MLA
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Seigler, H. F., Ward, F. E., Amos, D. B., Phaup, M. B., & Stickel, D. L. (1971). The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions. J Exp Med, 133(3), 411–423. https://doi.org/10.1084/jem.133.3.411
Seigler, H. F., F. E. Ward, D. B. Amos, M. B. Phaup, and D. L. Stickel. “The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions.J Exp Med 133, no. 3 (March 1, 1971): 411–23. https://doi.org/10.1084/jem.133.3.411.
Seigler HF, Ward FE, Amos DB, Phaup MB, Stickel DL. The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions. J Exp Med. 1971 Mar 1;133(3):411–23.
Seigler, H. F., et al. “The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions.J Exp Med, vol. 133, no. 3, Mar. 1971, pp. 411–23. Pubmed, doi:10.1084/jem.133.3.411.
Seigler HF, Ward FE, Amos DB, Phaup MB, Stickel DL. The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions. J Exp Med. 1971 Mar 1;133(3):411–423.

Published In

J Exp Med

DOI

ISSN

0022-1007

Publication Date

March 1, 1971

Volume

133

Issue

3

Start / End Page

411 / 423

Location

United States

Related Subject Headings

  • Time Factors
  • Skin Transplantation
  • Leukocytes
  • Immunology
  • Immunogenetics
  • Humans
  • Histocompatibility
  • Antigens
  • Alleles
  • 42 Health sciences