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Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum.

Publication ,  Journal Article
Stuhlmiller, GM; Boylston, JA; Seigler, HF; Fetter, BF
Published in: Am J Clin Pathol
June 1977

Three cases of metastatic malignant lesions are presented. By conventional pathologic examination these lesions were diagnosed as undifferentiated carcinomas. They were studied using a chimpanzee antiserum specific for human melanoma-associated antigens. In each case, cells from the tumor were reactive with the anti-melanoma antiserum. The tumors were also studied using the DOPA test. All three tumors were positive in the DOPA test, suggesting the presence of tyrosinase within the tumor cells. The results suggest that serologic identification of melanoma may provide a rapid, inexpensive means for tumor diagnosis.

Duke Scholars

Published In

Am J Clin Pathol

DOI

ISSN

0002-9173

Publication Date

June 1977

Volume

67

Issue

6

Start / End Page

573 / 579

Location

England

Related Subject Headings

  • Pathology
  • Pan troglodytes
  • Middle Aged
  • Melanoma
  • Male
  • Lymphatic Metastasis
  • Leukocyte Count
  • Immune Sera
  • Humans
  • Fluorescent Antibody Technique
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Stuhlmiller, G. M., Boylston, J. A., Seigler, H. F., & Fetter, B. F. (1977). Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum. Am J Clin Pathol, 67(6), 573–579. https://doi.org/10.1093/ajcp/67.6.573
Stuhlmiller, G. M., J. A. Boylston, H. F. Seigler, and B. F. Fetter. “Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum.Am J Clin Pathol 67, no. 6 (June 1977): 573–79. https://doi.org/10.1093/ajcp/67.6.573.
Stuhlmiller GM, Boylston JA, Seigler HF, Fetter BF. Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum. Am J Clin Pathol. 1977 Jun;67(6):573–9.
Stuhlmiller, G. M., et al. “Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum.Am J Clin Pathol, vol. 67, no. 6, June 1977, pp. 573–79. Pubmed, doi:10.1093/ajcp/67.6.573.
Stuhlmiller GM, Boylston JA, Seigler HF, Fetter BF. Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum. Am J Clin Pathol. 1977 Jun;67(6):573–579.
Journal cover image

Published In

Am J Clin Pathol

DOI

ISSN

0002-9173

Publication Date

June 1977

Volume

67

Issue

6

Start / End Page

573 / 579

Location

England

Related Subject Headings

  • Pathology
  • Pan troglodytes
  • Middle Aged
  • Melanoma
  • Male
  • Lymphatic Metastasis
  • Leukocyte Count
  • Immune Sera
  • Humans
  • Fluorescent Antibody Technique