Comparison of monoamine oxidase in golden hamster islets and insulinoma.
Journal Article
We compared the properties of monoamine oxidase (MAO) in hamster islets and insulinomas. The tryptamine concentration at which the monoamine oxidase velocity was half maximal (Km) was higher in islets than insulinomas; the maximal velocity (Vmax) of monoamine oxidase was greater in islets than insulinomas. Both islet and insulinoma are more sensitive to inhibition by pargyline than clorgyline. After pargyline administration the monoamine oxidase activity of insulinoma returns faster than activity of islets. This may occur because both synthesis of new MAO in pre-existing cells and formation of new cells occurs in the insulinoma.
Full Text
Duke Authors
Cited Authors
- Feldman, JM; Castleberry, CA; Vervaert, C; Seigler, HF
Published Date
- May 1, 1983
Published In
Volume / Issue
- 40 / 2
Start / End Page
- 307 - 320
PubMed ID
- 6308735
Pubmed Central ID
- 6308735
International Standard Serial Number (ISSN)
- 0034-5164
Language
- eng
Conference Location
- United States