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Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.

Publication ,  Journal Article
Meyers, WC; Seigler, HF; Hanks, JB; Thompson, WM; Postlethwait, R; Jones, RS; Akwari, OK; Cole, TB
Published in: Ann Surg
1980

The postoperative function of "free" jejunal autotransplants for replacement of the pharyngoesophagus after palliative resection was evaluated in nine patients using clinical assessment, cinefluoroscopy, manometry, and electrical studies. After an initial period of adjustment, all patients swallowed solids and liquids with minimal difficulty, gained weight appropriately and were satisfied with their operations. Cinefluoroscopy and esophageal manometry demonstrated normal function of the intact distal esophagus, which correlated with the absence of reflux symptoms. The grafts were capable of contraction in response to local distension and maintained an intrinsic myoelectrical activity. These results indicate that jejunal autotransplantation may provide excellent palliation with restoration of a near normal swallowing mechanism for patients with large resectable lesions of the pharyngoesophagus. An additional observation was that the instillation of food directly into the gastric antrum caused a change in the motor activity in the transplantd jejunum, indicating physiological hormonal control of intestinal motility.

Duke Scholars

Published In

Ann Surg

DOI

ISSN

0003-4932

Publication Date

1980

Volume

192

Issue

4

Start / End Page

439 / 450

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Surgery
  • Palliative Care
  • Muscle Contraction
  • Middle Aged
  • Manometry
  • Male
  • Jejunum
  • Humans
  • Female
 

Citation

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Meyers, W. C., Seigler, H. F., Hanks, J. B., Thompson, W. M., Postlethwait, R., Jones, R. S., … Cole, T. B. (1980). Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus. Ann Surg, 192(4), 439–450. https://doi.org/10.1097/00000658-198010000-00002
Meyers, W. C., H. F. Seigler, J. B. Hanks, W. M. Thompson, R. Postlethwait, R. S. Jones, O. K. Akwari, and T. B. Cole. “Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.Ann Surg 192, no. 4 (1980): 439–50. https://doi.org/10.1097/00000658-198010000-00002.
Meyers WC, Seigler HF, Hanks JB, Thompson WM, Postlethwait R, Jones RS, et al. Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus. Ann Surg. 1980;192(4):439–50.
Meyers, W. C., et al. “Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.Ann Surg, vol. 192, no. 4, 1980, pp. 439–50. Pubmed, doi:10.1097/00000658-198010000-00002.
Meyers WC, Seigler HF, Hanks JB, Thompson WM, Postlethwait R, Jones RS, Akwari OK, Cole TB. Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus. Ann Surg. 1980;192(4):439–450.

Published In

Ann Surg

DOI

ISSN

0003-4932

Publication Date

1980

Volume

192

Issue

4

Start / End Page

439 / 450

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Surgery
  • Palliative Care
  • Muscle Contraction
  • Middle Aged
  • Manometry
  • Male
  • Jejunum
  • Humans
  • Female