Constituents from the root and stem of Aristolochia elegans.

Published

Journal Article

Four new tetralones, aristelegone-A (1), aristelegone-B (2), aristelegone-C (3), and aristelegone-D (4); one new isoquinoline, pericampylinone-A (5); four new biphenyl ethers, aristogin-A (6), aristogin-B (7), aristogin-D (8), and aristogin-E (9); three new lignans, aristelegin-A (10), aristelegin-B (11), and aristelegin-C (12); and a new dimer, aristolin (13), have been isolated from the root and stem of Aristolochia elegans. The structures were established on the basis of 1D and 2D NMR and mass spectral data. This is the first report of isoquinolones and biphenyl ethers from this plant which may be representative units for the formation of bisbenzylisoquinoline alkaloids that are common metabolites of Aristolochia species. Aristolin (13) is also the first report of a diterpene linked with an aristolochic acid.

Full Text

Duke Authors

Cited Authors

  • Wu, T-S; Tsai, Y-L; Damu, AG; Kuo, P-C; Wu, P-L

Published Date

  • November 2002

Published In

Volume / Issue

  • 65 / 11

Start / End Page

  • 1522 - 1525

PubMed ID

  • 12444670

Pubmed Central ID

  • 12444670

International Standard Serial Number (ISSN)

  • 0163-3864

Digital Object Identifier (DOI)

  • 10.1021/np020218u

Language

  • eng

Conference Location

  • United States